Agents of S.H.I.E.L.D. opens up with Coulson and Mace conducting a plan to trick a Hydra transport that they believe contains Daisy inside. They take down the Hydra driver, but they don’t find Daisy inside of it. Instead, they find several body bags at the back of the vehicle. Once back at S.H.I.E.L.D., Ward is relieved that Daisy wasn’t in any of those bags. Mack is still getting adjusted to the environment as he still doesn’t remember his life back in the real world. Simmons tries to get Coulson to help her find Daisy quicker so they can get out of the Framework, but Coulson stresses that they need Mace’s help. Coulson admits that he is still getting a weird feeling about Ward and Simmons reminds him about the history the two of them had in the real world.
Over at Hydra, the Madame and May are discussing that the Inhuman population is growing and that they need to put an end to it. May visits a Hydra scientist who has a temporary strength serum that will let her go toe-to-toe with The Patriot. A beaten up Daisy gets a visit by Fitz who tells her that he hasn’t told anyone about her Inhuman DNA. Fitz demands that Skye tells him where The Patriot is and whether he is also from “the real world”. Skye tries to get through to Fitz by reminding him of the love he has for Simmons, but that leads to her getting punched. Fitz promises that he won’t let her ruin his home. Madame Hydra decides to give it a try and tells Fitz to go and look over Project Looking Glass. She enters the room and starts telling Skye about how the Framework was designed, where she fixed a big regret in each of their lives. The Madame tries to convey Skye that she can live a happy life in the Framework, in exchange for where their bodies are back in the real world.
Fitz is seen speaking with a Scottish man who is wondering what is bothering him and we see later Fitz confessing to him that he shot Agnes. It’s revealed that this mystery man is none other than Fitz’s man, although no name is given or if he is actually real. We cut back to Skye who hears Radcliffe in the cell on the other side of the wall as he is screaming and crying. She finds out from Radcliffe that Fitz killed Agnes and gets stunned that he actually went through with it. Skye and Radcliffe start discussing about how a single regret in a life can change so many outcomes in someone’s life. Back at S.H.I.E.L.D., Ward and Mace interrogates Simmons again who is telling Mace about his catch phrase in the real world. Mace asks if they were close in the real world, where he is from and all sorts of questions. Despite all of his questions, Mace and Ward are still not buying Simmons’ story about the real world as Ward questions how she can be so sure that this world is fake. Later on, Coulson is given a fake Hydra badge by Mace as they are going to try to save Daisy. They manage to break in and Mace saves an old friend: Anthony Triplet!
He starts looking his boots as Trip claims there is something important inside one of them that he needs. Trip finds the knocked-out Hydra soldier wearing them, as Coulson sees his student that got taken from his history class and decides to go after him. However, May arrives, who is all juiced up, starts fighting Mace who notices that she is different. Mace gets away and May is determined more than ever to stop Mace. Coulson finds several teenagers as they are being brain washed by Hydra and gets help by Trip to get them out. However Hydra starts to destroy the buildings and May is stunned that there were kids being kept there as prisoners. May finds herself helping Coulson and his team to get the kids out of the building. As the building keeps shaking and falling, Mace keeps it up long enough for them all to get out, before it crumbles all together with him trapped inside.
We cut back to the real world where Mace has officially passed away as we get reminded that when you die in the Framework, you die for real. The episode ends with May walking into Skye’s cell where she asks her if it’s true that Skye is an Inhuman. Skye confesses and tells May that she is powerful enough to bring the whole place down. May says that she hopes that is true as she crushes a Terrigen Crystal, Skye gets covered in Terrigen Mist with the two women nodding to each other, implying that maybe, May has awaken.
With so much going down in this episode, we have a lot to discuss. With all of that said, hit the NEXT button below and let’s go through some of tonight’s biggest highlights and important moments in the Agents of S.H.I.E.L.D. Season 4 episode: “No Regrets”