In the Batman Versus Predator crossover, Batman is called in to investigate a mysterious murder of a boxer. As he investigates the crime, the Predator makes his presence known and attacks even more people in Gotham City. After a quick skirmish, the Caped Crusader is left bruised and beaten, but he perseveres to defend his city.
With the help of a custom exoskeleton, Batman takes the fight to the Predator and lays on the pain. Their battle stretches on for a long time and over multiple locations. After a chase with the Batmobile, the fight ends outside Wayne Manor. Ultimately, Batman takes the Predator down and beats him with a metal baseball bat. The Predator ends up committing an honor suicide in front of other Predators in a sign of respect for the Caped Crusader that was able to take him down. The Predators left for a bit, but there were two sequel series that saw him fight more of them.